Malabsorption syndrome aggravates calcium homeostasis impairment in chronic kidney disease patients
نویسندگان
چکیده
Abstract. Recent data on the role of digestive pathology in progression chronic kidney disease (CKD) remain scarce. Calcium homeostasis plays an important renal pathology, especially patients with malabsorption syndrome (MAS).
 The research aimed to evaluate calcium CKD MAS.
 Methods. In this cross-sectional observational study, 99 MAS were enrolled. divided into 4 groups according stage and presence MAS. Group I included 25 stages 1 2 without MAS; II consisted 26 2, ІІІ (n = 23) ІV 25) 3 MAS, respectively. According morphological study vivo biopsies small intestinal mucosa, mild moderate changes observed among all patients. levels calcium, phosphorus, parathyroid hormone, osteocalcin, calcitonin blood, as well urinary levels, detected.
 Results. Pathological metabolism severity disorders was more evident compared 2. Urinary reduced Groups III IV. No detected phosphorus levels. Changes hormone osteocalcin are caused primarily by combined impaired absorption.
 Conclusion. leads deep violations resulting rapid bone tissue violation.
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ژورنال
عنوان ژورنال: Ukraïns?kij žurnal nefrologìï ta dìalìzu
سال: 2022
ISSN: ['2616-7352', '2304-0238']
DOI: https://doi.org/10.31450/ukrjnd.2(74).2022.05